Clinical Papers
High levels of fluoride create insoluble calcium fluorite
Fluoride levels above 45ppm lead to the formation of insoluble Calcium Fluoride (fluorite).
At and below 45 ppm [F–] in the solution, F MAS-NMR showed fluoride-substituted apatite formation, and above 45 ppm, calcium fluoride (CaF2) formed in increasing proportions. Further increases in [F–] caused no further reduction in demineralization, but increased the proportion of CaF2 formed.
Remineralisation / treatment comparison at 1450, 5000, 9000 ppm fluoride levels
BioMin F compared to NovaMin (Sensodyne Repair & Protect) containing dentifrice a comparison of fluoride content and remineralisation capability
Biomin F® toothpaste demonstrated more fluoride content and greater potential to promote remineralization of demineralized human enamel compared to Novamin®. BiominF toothpaste presented higher micro-hardness values on remineralization. BioMin F packaged fluoride content is 530 ppm vs NovaMin containing toothpaste at 1,450ppm.
BioMin can Remineralise White Spot Lesions Surrounding Orthodontic Brackets
Biomin paste has a high capacity to remineralize white spot lesions associated with orthodontic brackets when compared to fluoride application.
BioMin F showed a remineralisation rate 2X (twice) that of Colgate 1450 ppm toothpaste
A head to head comparison of BioMin F vs 1450 ppm Colgate monofluorophosphate toothpaste. BioMin showed a significantly greater remineralisation rate (Δ 118.73 vs Δ 60.54) measured using mean Vickers Hardness Number.
BioMin F vs Colgate 1450 ppm toothpaste - remineralisation comparison
BioMin F in comparison to Colgate 1450 ppm fluoride toothpaste, delivers a greater surface micro hardness, a smoother enamel surface and greater enamel volume restoration (remineralisation)Â .
The effect of different concentrations of fluoride in toothpastes with or without bioactive glass on artificial root caries. BioMin vs 1450, 5000 ppm)
Note: This methodology had BioMin rinsed post application, which against protocols and may affect performance.
The highest KHN (Knoop Hardness Test) values were observed in Group-1. (BioMin F) This could be related to the ability of bioglass within the toothpastes to release calcium and phosphate with fluoride ions to promote remineralisation. In this respect, it was reported that bioglass has the ability to act as a nucleating agent and re-attract calcium and phosphate ions forming hard with acid-resistant layer in a form of hydroxyl‑like crystals on the tooth surface. The bioactive bioglass (BG) used in this study forms fluorapatite and in the presence of apatite
BioMin effectively remineralises white spot lesions, 95% higher remin rate than 9,000 ppm gel. Low fluoride enables subsurface remin.
The low fluoride content of the BioMin FÂ (vs. 9,000 ppm fluoride gel), allowed the penetration of BioMin FÂ rich content of calcium and phosphate through the porous enamel sub-surface, causing the re-mineralization of the demineralized enamel lesion rather than remineralizing the outer enamel surface.